InterPro domain: IPR036881

Glycoside hydrolase family 3 GH3 comprises enzymes with a number of known activities; beta-glucosidase ( 3.2.1.21 ); beta-xylosidase ( 3.2.1.37 ); N-acetyl beta-glucosaminidase ( 3.2.1.52 ); glucan beta-1,3-glucosidase ( 3.2.1.58 ); cellodextrinase( 3.2.1.74 ); exo-1,3-1,4-glucanase ( 3.2.1 ).

These enzymes are two-domain globular proteins that are N-glycosylated at three sites [ 1 ]. This entry represents the C-terminal domain superfamily, involved in catalysis and may be involved in binding beta-glucan [ 2 ]. Its structure has a flavodoxin-like fold, which consists of three layers (alpha/beta/alpha) with parallel beta-sheet of five strand.

1. Three-dimensional structure of a barley beta-D-glucan exohydrolase, a family 3 glycosyl hydrolase. Structure 7, 179-90