InterPro domain: IPR036849

General Information

  • Identifier IPR036849
  • Description Enolase-like, C-terminal domain superfamily
  • Number of genes 856
  • Gene duplication stats Loading...

Abstract

The C-terminal domain of the enolase adopts a TIM barrel fold that contains a metal binding site [ 1 ]. Proteins containing this domain also include D-glucarate dehydratase-like proteins and some uncharacterised proteins [ 2 ].


1. The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. J. Biol. Chem. 277, 8306-11
2. Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity. Arch. Biochem. Biophys. 433, 59-70

Species distribution

Gene table