InterPro domain: IPR036747

General Information

  • Identifier IPR036747
  • Description Histone chaperone ASF1-like superfamily
  • Number of genes 214
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005634   GO:0006333  

Abstract

This family includes the yeast and human ASF1 protein. These proteins have histone chaperone activity [ 1 ]. ASF1 participates in both the replication-dependent and replication-independent pathways. The structure three-dimensional has been determined as a compact immunoglobulin-like beta sandwich fold topped by three helical linkers [ 2 ].


1. Structure and function of the conserved core of histone deposition protein Asf1. Curr. Biol. 13, 2148-58
2. A human homologue of yeast anti-silencing factor has histone chaperone activity. Genes Cells 5, 221-33

Species distribution

Gene table