InterPro domain: IPR036735

This is the N-terminal domain superfamily of transcription termination/antitermination protein NusG, which is involved in transcription elongation, termination and antitermination. It also occurs at the N-terminal of transcription antitermination protein RfaH and in the transcription elongation factor Spt5 [ 1 ]. This domain has a Ferredoxin-like fold, which consists of an alpha+beta sandwich with antiparallel beta-sheet.

1. Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation. Structure 16, 1649-58