InterPro domain: IPR036660
General Information
- Identifier IPR036660
- Description Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily
- Number of genes 2
- Gene duplication stats Loading...
- Associated GO terms GO:0016836
Abstract
This entry represents various Fe-S type hydro-lyases, including the beta subunit from both L-tartrate dehydratase (TtdB; 4.2.1.32 ) and class 2 fumarate hydratase (FumC; 4.2.1.2 ) [ 1 ]. A number of Fe-S cluster-containing hydro-lyases share a conserved motif, including argininosuccinate lyase, adenylosuccinate lyase, aspartase, class I fumarate hydratase (fumarase), and tartrate dehydratase (see IPR000362 ). Proteins in this group represent a subset of closely related proteins or modules, including the Escherichia coli tartrate dehydratase beta chain and the C-terminal region of the class I fumarase (where the N-terminal region is homologous to the tartrate dehydratase alpha chain). The activity of the archaeal proteins in this group is unknown.
1. Molecular cloning and functional characterization of fumarases C in Neisseria species. Antonie Van Leeuwenhoek 87, 205-13