InterPro domain: IPR036635

General Information

  • Identifier IPR036635
  • Description UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily
  • Number of genes 52
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008762  

Abstract

This entry represents a C-terminal conserved region of UDP-N-acetylenolpyruvoylglucosamine reductase 1.1.1.158 , which is also called UDP-N-acetylmuramate dehydrogenase. The C-terminal domain is involved in substrate binding [ 1 ]. It is a part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide, which is a precursor of bacterial peptidoglycan.


1. (E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Biochemistry 35, 1342-51

Species distribution

Gene table