InterPro domain: IPR036037

General Information

  • Identifier IPR036037
  • Description Class XVII myosin, motor domain
  • Number of genes 1
  • Gene duplication stats Loading...

Abstract

Mcs1, also known as chitin synthase 8, is a fungal protein that contains a myosin-17 motor domain and can travel along both microtubules and F-actin. Mcs1 works in cooperation with myosin-5 and kinesin-1 and in opposition to dynein in the secretion of cell wall-forming fungal chitin synthases. Successful exocytosis requires the motor domain of Mcs1, which captures and tethers the vesicles prior to secretion [ 1 , 2 ].


1. Myosin-5, kinesin-1 and myosin-17 cooperate in secretion of fungal chitin synthase. EMBO J. 31, 214-27
2. Motors in fungal morphogenesis: cooperation versus competition. Curr. Opin. Microbiol. 14, 660-7

Species distribution

Gene table