InterPro domain: IPR035417

General Information

  • Identifier IPR035417
  • Description FACT complex subunit POB3-like, N-terminal PH domain
  • Number of genes 158
  • Gene duplication stats Loading...

Abstract

This domain is found at the N terminus of POB3 and related proteins [ 1 ]. POB3 is a subunit of the heterodimeric yeast FACT complex involved in transcriptional initiation [ 2 ] and a homologue of metazoan SSRP1 protein [ 3 ].


1. Structural basis of histone H2A-H2B recognition by the essential chaperone FACT. Nature 499, 111-4
2. The yeast FACT complex has a role in transcriptional initiation. Mol. Cell. Biol. 25, 5812-22
3. The FACT chromatin modulator: genetic and structure/function relationships. Biochem. Cell Biol. 82, 419-27

Species distribution

Gene table