InterPro domain: IPR035010
General Information
- Identifier IPR035010
- Description Dual specificity protein phosphatase PHS1
- Number of genes 166
- Gene duplication stats Loading...
- Associated GO terms GO:0004721 GO:0009737 GO:0043622
Abstract
PHS1 is dual-specificity phophosphatase from plants. It specifically interacts with two MAPKs, MPK12 and MPK18. PHS1-MPK18 signalling probably regulates cortical microtubule functions [ 1 , 2 ]. It is also a negative regulator of abscisic acid (ABA) signalling [ 3 ]. Plant hormone ABA control numeros processes, such as dormancy and germination of seeds, senescence and resistance to abiotic stresses.
1. Arabidopsis mitogen-activated protein kinase MPK18 mediates cortical microtubule functions in plant cells. Plant J. 59, 565-75
2. A semidominant mutation in an Arabidopsis mitogen-activated protein kinase phosphatase-like gene compromises cortical microtubule organization. Plant Cell 16, 1841-53
3. The phs1-3 mutation in a putative dual-specificity protein tyrosine phosphatase gene provokes hypersensitive responses to abscisic acid in Arabidopsis thaliana. Plant J. 47, 711-9