InterPro domain: IPR034603

Enzymes in the dipeptide epimerase family catalyze the epimerization of dipeptides, with the preferred substrate often L-Ala-D/L-Glu. Based on genomic context and substrate specificity, these enzymes may be involved in metabolism of the murein peptide, of which L-Ala-D-Glu is a component [ 1 , 2 ].

1. Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening. Structure 16, 1668-77
2. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc. Natl. Acad. Sci. U.S.A. 109, 4122-7