InterPro domain: IPR034150

This entry represents the RNA recognition motif (RRM) of SF3B14 (p14), also known as splicing factor 3B subunit 6 (SF3B6), which is part of the SF3B complex that is an integral part of the U2 small nuclear ribonucleoprotein (snRNP) and the U11/U12 di-snRNP [ 1 ]. SF3B14 associates directly with another SF3B subunit called SF3B155 [ 2 ]. SF3B14 can be cross-linked to the branch-point adenosine of pre-mRNA introns within the spliceosome [ 3 ].

1. Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA 12, 410-25
2. Structural model of the p14/SF3b155 · branch duplex complex. RNA 17, 155-65