InterPro domain: IPR034138

General Information

  • Identifier IPR034138
  • Description Nucleolar protein 8, RNA recognition motif
  • Number of genes 86
  • Gene duplication stats Loading...

Abstract

This entry represents the RNA recognition motif of NOP8 (also known as NOP132). In humans, NOP132 associates with proteins involved in ribosome biogenesis and RNA metabolism, including the DEAD-box RNA helicase protein, DDX47 [ 1 ]. Budding yeast NOP8 is required for 60S ribosomal subunit synthesis [ 2 ].


1. NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47. Nucleic Acids Res. 34, 4593-608
2. Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p. Mol. Cell. Biol. 19, 1518-25

Species distribution

Gene table