InterPro domain: IPR034110

General Information

  • Identifier IPR034110
  • Description LSM domain containing 1
  • Number of genes 109
  • Gene duplication stats Loading...
  • Associated GO terms GO:0031417  

Abstract

LSM domain containing 1, also known as Mak31 or Naa38, is the auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues [ 1 ].

LSMD1 proteins have a single Sm-like domain structure. Sm-like proteins exist in archaea as well as bacteria, forming heptameric and hexameric ring structures similar to those found in eukaryotes [ 2 ].


1. NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p. J. Biol. Chem. 276, 20154-9
2. Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J. 18, 3451-62

Species distribution

Gene table