InterPro domain: IPR033708

General Information

  • Identifier IPR033708
  • Description Isoleucyl tRNA synthetase type 1, anticodon-binding domain
  • Number of genes 116
  • Gene duplication stats Loading...
  • Associated GO terms GO:0000049  

Abstract

This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA [ 1 ].


1. Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science 285, 1074-7

Species distribution

Gene table