InterPro domain: IPR033708
General Information
- Identifier IPR033708
- Description Isoleucyl tRNA synthetase type 1, anticodon-binding domain
- Number of genes 116
- Gene duplication stats Loading...
- Associated GO terms GO:0000049
Abstract
This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA [ 1 ].
1. Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science 285, 1074-7
Species distribution
Gene table
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