InterPro domain: IPR033551

General Information

  • Identifier IPR033551
  • Description Dynein regulatory complex subunit 7
  • Number of genes 8
  • Gene duplication stats Loading...

Abstract

DRC7 or coiled-coil domain-containing protein 135 (CCD135), known as lobo in Drosophila, is a protein involved in flagelar motility [ 1 ]. It is a component of the nexin-dynein regulatory complex, which is an important regulatory node of dynein activity [ 2 ]. Lobo is involved in Drosophila sperm motility [ 3 ].


1. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Mol. Biol. Cell 22, 976-87
2. Building blocks of the nexin-dynein regulatory complex in Chlamydomonas flagella. J. Biol. Chem. 286, 29175-91

Species distribution

Gene table