InterPro domain: IPR033551
General Information
- Identifier IPR033551
- Description Dynein regulatory complex subunit 7
- Number of genes 8
- Gene duplication stats Loading...
Abstract
DRC7 or coiled-coil domain-containing protein 135 (CCD135), known as lobo in Drosophila, is a protein involved in flagelar motility [ 1 ]. It is a component of the nexin-dynein regulatory complex, which is an important regulatory node of dynein activity [ 2 ]. Lobo is involved in Drosophila sperm motility [ 3 ].
1. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Mol. Biol. Cell 22, 976-87
2. Building blocks of the nexin-dynein regulatory complex in Chlamydomonas flagella. J. Biol. Chem. 286, 29175-91
Species distribution
Gene table
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