InterPro domain: IPR033511

General Information

  • Identifier IPR033511
  • Description Rho guanine nucleotide exchange factor Cdc24/Scd1, PH domain
  • Number of genes 1
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005085  

Abstract

This entry represents the PH domain found in Cdc24 from budding yeasts and Scd1 from fission yeasts. Cdc24 and Scd1 are guanine nucleotide exchange factors (GEFs) for Cdc42 [ 1 , 2 ].


1. Gef1p and Scd1p, the Two GDP-GTP exchange factors for Cdc42p, form a ring structure that shrinks during cytokinesis in Schizosaccharomyces pombe. Mol. Biol. Cell 14, 3617-27
2. Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3. J. Biol. Chem. 269, 2369-72

Species distribution

Gene table