InterPro domain: IPR033371

General Information

  • Identifier IPR033371
  • Description Arginine and glutamate-rich protein 1
  • Number of genes 233
  • Gene duplication stats Loading...

Abstract

The arginine and glutamate-rich 1 (ARGLU1) family of proteins is found in metazoa and plants. In mammals, ARGLU1 cooperates with MED1 to regulate estrogen receptor-mediated gene transcription [ 1 ].


1. Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growth. J. Biol. Chem. 286, 17746-54

Species distribution

Gene table