InterPro domain: IPR033336

General Information

  • Identifier IPR033336
  • Description Stabilizer of axonemal microtubules 1/2
  • Number of genes 7
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008017  

Abstract

Stabilizer of axonemal microtubules 1/2 (SAXO1/2) may play a role in the regulation of cilium length. Human SAXO1 binds specifically to centriole and cilium microtubules. It stabilizes microtubules at low temperature [ 1 ].


1. Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures. J. Cell. Sci. 128, 1294-307

Species distribution

Gene table