InterPro domain: IPR032845

General Information

  • Identifier IPR032845
  • Description U11/U12 small nuclear ribonucleoprotein 48kDa protein
  • Number of genes 124
  • Gene duplication stats Loading...

Abstract

Proteins in this family are likely involved in U12-type 5' splice site recognition [ 1 ]. U12-introns constitute a small fraction of all introns, but they have been identified in various genes implicated in biologically important processes [ 2 ].


1. Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure 17, 294-302
2. Splicing of a rare class of introns by the U12-dependent spliceosome. Biol. Chem. 386, 713-24

Species distribution

Gene table