InterPro domain: IPR032792

This is a glucanotransferase catalytic domain of the glycogen debranching enzyme AGL. AGL is a multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation [ 1 ]. This glucanotransferase domain is predicted to have a structure of a 8 stranded alpha/beta barrel (TIM barrel) where strands are interrupted by long loops and additional mini-domains.

1. The Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme. FEMS Yeast Res. 11, 499-508