InterPro domain: IPR032781

In E.coli four ABC-F proteins have been characterised: EttA, YbiT, YheS, and Uup. EttA was shown to interact with the ribosome ( IPR022374 ). YbiT, YheS, and Uup have also been shown to bind to the ribosome [ 1 ].

This domain is an extension of some members of IPR003439 and other ABC-transporter families. It is not responsible for ribosome binding, but it is used by proteins which bind to the ribosome to stabilise the interaction.

1. ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life. J. Mol. Biol. 431, 3568-3590