InterPro domain: IPR032198

General Information

  • Identifier IPR032198
  • Description E2F transcription factor, CC-MB domain
  • Number of genes 396
  • Gene duplication stats Loading...
  • Associated GO terms GO:0046983  

Abstract

This is the coiled coil (CC) - marked box (MB) domain of E2F transcription factors. This domain forms a heterodimer with the corresponding domain of the DP transcription factor, the heterodimer binds the C terminus of retinoblastoma protein [ 1 ].


1. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell 123, 1093-106

Species distribution

Gene table