InterPro domain: IPR032191

General Information

  • Identifier IPR032191
  • Description CCR4-NOT transcription complex subunit 1, CAF1-binding domain
  • Number of genes 197
  • Gene duplication stats Loading...

Abstract

This is the CAF1-binding domain of CCR4-NOT transcription complex subunit 1, which is a scaffolding component of the CCR4-NOT complex. This domain adopts a MIF4G (middle portion of eIF4G) fold [ 1 ].


1. The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex. Nucleic Acids Res. 40, 11058-72

Species distribution

Gene table