InterPro domain: IPR031937

General Information

  • Identifier IPR031937
  • Description PNN-interacting serine/arginine-rich protein
  • Number of genes 98
  • Gene duplication stats Loading...

Abstract

Pinin (PNN) has been identified as central in the establishment and maintenance of corneal epithelial cell-cell adhesion. Three SR-rich proteins have been identified that interact with the C terminus of PNN; one of them is this 130kDa nuclear protein, SRrp130, also known as PNISR [ 1 ]. SRrp130 is a protein of 805 amino acid residues with multiple arginine-serine (RS) repeats but had no RNA recognition motif [ 2 ]. Its function is unknown.


1. Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 44, 4715-23

Species distribution

Gene table