InterPro domain: IPR031916

General Information

  • Identifier IPR031916
  • Description DNA ligase 3, BRCT domain
  • Number of genes 9
  • Gene duplication stats Loading...

Abstract

The BRCT domain of DNA ligase 3 (LIG3) binds to the C-terminal BRCT domain of the scaffolding protein X-ray repair cross-complementing protein 1 (XRCC1) and mediates homo- and heterodimerisation [ 1 ].


1. The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes. Nucleic Acids Res. 39, 7816-27

Species distribution

Gene table