InterPro domain: IPR031737
General Information
- Identifier IPR031737
- Description Condensin-2 complex subunit H2, C-terminal
- Number of genes 131
- Gene duplication stats Loading...
Abstract
This entry represents the C-terminal domain of the H2 subunit of the condensin II complex (Ncaph2), found in eukaryotes but not fungi.
Condensin complexes are involved in the restructuring and maintenance of chromatin. Eukaryotes possess two condensins (condensin I and condensin II), each composed of structural maintenance of chromosomes proteins SMC2 and SMC4, with three additional non-SMC condensin-associated proteins (Ncaps) unique to each condensin (condensin I - Ncaph, Ncapd2, and Ncapg; condensin II - Ncaph2, Ncapd3, and Ncapg2) [ 1 , 2 ].
1. Condensin and cohesin complexity: the expanding repertoire of functions. Nat. Rev. Genet. 11, 391-404
2. Condensins: universal organizers of chromosomes with diverse functions. Genes Dev. 26, 1659-78