InterPro domain: IPR031192

General Information

  • Identifier IPR031192
  • Description DIS3-like exonuclease 1

Abstract

DIS3-like exonuclease 1 (DIS3L) is an exosome-associated exoribonuclease [ 1 ]. The eukaryotic RNA exosome is a ribonucleolytic complex involved in RNA processing and turnover [ 2 ].


1. Dis3-like 1: a novel exoribonuclease associated with the human exosome. EMBO J. 29, 2358-67
2. The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L. EMBO J. 29, 2342-57

Species distribution

Gene table