InterPro domain: IPR031055
General Information
- Identifier IPR031055
- Description Protein rough sheath 2 /ASYMMETRIC LEAVES1
- Number of genes 123
- Gene duplication stats Loading...
- Associated GO terms GO:0005634 GO:0006351 GO:0010338
Abstract
This entry represents a group of Myb transcription factors from plants, including protein rough sheath 2 (RS2) and ASSYMMETRIC LEAVES1 (Asn1) [ 1 , 2 ]. They repress Knotted1-type homeobox (KNOX) genes and are required to establish determinacy during leaf development. RS2/AS1 interacts with the DNA binding factor ASYMMETRIC LEAVES2, a predicted RNA binding protein (RIK, for RS2-Interacting KH protein), and a homologue of the chromatin-remodeling protein HIRA. Together with HIRA, RS2/AS1 mediates the epigenetic silencing of knox genes, possibly by modulating chromatin structure [ 3 ].
1. Conservation and molecular dissection of ROUGH SHEATH2 and ASYMMETRIC LEAVES1 function in leaf development. Proc. Natl. Acad. Sci. U.S.A. 100, 6837-42
2. Functional conservation of wheat orthologs of maize rough sheath1 and rough sheath2 genes. Plant Mol. Biol. 69, 273-85
3. Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis. Plant Cell 17, 2886-98