InterPro domain: IPR031008

General Information

  • Identifier IPR031008
  • Description Phenylalanine aminomutase (L-beta-phenylalanine forming)
  • Number of genes 2
  • Gene duplication stats Loading...

Abstract

Members of this family are the phenylalanine aminomutase known from taxol biosynthesis [ 1 ]. This enzyme has the MIO prosthetic group (4-methylideneimidazole-5-one), derived from an Ala-Ser-Gly motif. Other MIO enzymes include Phe, Tyr, and His ammonia-lyases. This entry serves as an exception to overrule assignments by IPR005922 for phenylalanine ammonia-lyase.


1. Cloning, heterologous expression, and characterization of a phenylalanine aminomutase involved in Taxol biosynthesis. J. Biol. Chem. 279, 53947-54

Species distribution

Gene table

Loading...