InterPro domain: IPR030802

General Information

  • Identifier IPR030802
  • Description ABC transporter permease MalE
  • Number of genes 137
  • Gene duplication stats Loading...
  • Associated GO terms GO:0043190  

Abstract

Intermembrane phospholipid transport system permease protein MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane [ 1 ]. In Q7DD59 it is involved in L-glutamate import into the cell [ 2 ]. In Q8L4R0 it is involved in lipid transfer within the cell [ 3 ]. Many bacterial species have one or two members from this family. The Mycobacteria have large paralogous families included in this entry [ 4 , 4 ].


1. An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc. Natl. Acad. Sci. U.S.A. 106, 8009-14
2. Identification of a meningococcal L-glutamate ABC transporter operon essential for growth in low-sodium environments. Infect. Immun. 74, 1725-40
3. A permease-like protein involved in ER to thylakoid lipid transfer in Arabidopsis. EMBO J. 22, 2370-9

Species distribution

Gene table

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