InterPro domain: IPR030300
General Information
- Identifier IPR030300
- Description Signal recognition particle 43kDa protein
- Number of genes 102
- Gene duplication stats Loading...
- Associated GO terms GO:0009507 GO:0080085 GO:0045038 GO:0009416
Abstract
This entry represents chloroplast signal-recognition particle 43kDa protein (CpSRP43). In Arabidopsis, CpSRP43 (AT2G47450, CAO) is a component of the chloroplast signal recognition particle pathway that is involved in LHCP (light-harvesting chlorophyll a/b-binding protein) targeting. LHCPs are synthesised in the cytoplasm, and after import into the chloroplast, they are targeted and inserted into the thylakoid membrane. In addition, CpSRP43 functions as a chaperone preventing aggregation of LHCP following import into the chloroplast [ 1 , 2 ].
1. Mechanism of an ATP-independent protein disaggregase: I. structure of a membrane protein aggregate reveals a mechanism of recognition by its chaperone. J. Biol. Chem. 288, 13420-30
2. cpSRP43 is a novel chaperone specific for light-harvesting chlorophyll a,b-binding proteins. J. Biol. Chem. 285, 21655-61