InterPro domain: IPR029488
General Information
- Identifier IPR029488
- Description Hemingway/CFA97
- Number of genes 7
- Gene duplication stats Loading...
Abstract
Drosophila Hemingway (Hmw) is required for motile cilia function and sperm flagella assembly [ 1 ]. The human orthologue, known as cilia- and flagella-associated protein 97 (CFAP97) or KIAA1430, localises to the primary cilium [ 2 ]. Another member of this family is the uncharacterised protein CFAP97D1/2 (CFAP97 domain-containing protein 1/2).
1. hemingway is required for sperm flagella assembly and ciliary motility in Drosophila. Mol. Biol. Cell 25, 1276-86
2. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Cell 163, 1484-99
Species distribution
Gene table
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