InterPro domain: IPR029488

General Information

  • Identifier IPR029488
  • Description Hemingway/CFA97
  • Number of genes 7
  • Gene duplication stats Loading...

Abstract

Drosophila Hemingway (Hmw) is required for motile cilia function and sperm flagella assembly [ 1 ]. The human orthologue, known as cilia- and flagella-associated protein 97 (CFAP97) or KIAA1430, localises to the primary cilium [ 2 ]. Another member of this family is the uncharacterised protein CFAP97D1/2 (CFAP97 domain-containing protein 1/2).


1. hemingway is required for sperm flagella assembly and ciliary motility in Drosophila. Mol. Biol. Cell 25, 1276-86
2. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Cell 163, 1484-99

Species distribution

Gene table

Loading...