InterPro domain: IPR029045

General Information

  • Identifier IPR029045
  • Description ClpP/crotonase-like domain superfamily
  • Number of genes 5280
  • Gene duplication stats Loading...

Abstract

This superfamily represents a ClpP/crotonase-like domain formed from repeated beta/beta/alpha units, which comprises two perpendicular beta-sheet surrounded by alpha-helices. Proteins containing this domain can be classified into four structural families [ 1 ]:

  • The Clp protease, Clp subunit family.
  • The tail-specific protease, catalytic domain family. Members include tricorn proteases.
  • The crotonase-like family.
  • The biotin-dependent carboxylase carboxyltransferase domain family. Members include the acetyl-coenzyme A carboxylase carboxyl transferase subunits.


1. Mechanisms and structures of crotonase superfamily enzymes--how nature controls enolate and oxyanion reactivity. Cell. Mol. Life Sci. 65, 2507-27

Species distribution

Gene table

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