InterPro domain: IPR029039

Proteins in this entry contain a flavodoxin-like fold, which is characterised by an open twisted/alpha beta structure consisting of five parallel beta-sheets connected by alpha-helices which surround the sheet. Flavodoxins are electron-transfer proteins that function in various electron transport systems. They bind one FMN molecule, which serves as a redox-active prosthetic group and are functionally interchangeable with ferredoxins [ 1 ].

This domain superfamily can be found in flavodoxins, FMN-dependent NADH-azo compound oxidoreductases, ribonucleotide reductase stimulatory proteins, glutathione-regulated potassium-efflux system ancillary protein KefG, N-terminal of the sulfite reductase [NADPH] flavoprotein alpha-component and the C-terminal of the anaerobic nitric oxide reductase flavorubredoxin.

1. The amino acid sequence of a flavodoxin from the eukaryotic red alga Chondrus crispus. Biochem. J. 263, 981-4