InterPro domain: IPR029004

Ribosomal protein L28e forms part of the 60S ribosomal subunit [ 1 ]. This family is found in eukaryotes. In rat there are 9 or 10 copies of the L28 gene. The L28 protein contains a possible internal duplication of 9 residues [ 2 ].

In budding yeast, Mak16 forms part of the 66S pre-ribosomal particles and functions as a transacting actor involved in rRNA processing [ 3 , 4 ].

This entry represents a ribosomal L28e domain that also matches the N-terminal region of Mak16.

1. The primary structure of rat ribosomal protein L38. Biochem. Biophys. Res. Commun. 175, 551-5
2. The primary structure of rat ribosomal proteins: the amino acid sequences of L27a and L28 and corrections in the sequences of S4 and S12. Biochim. Biophys. Acta 1050, 69-73
3. Yeast virus propagation depends critically on free 60S ribosomal subunit concentration. Mol. Cell. Biol. 15, 2772-81
4. Mak16p is required for the maturation of 25S and 5.8S rRNAs in the yeast Saccharomyces cerevisiae. Yeast 23, 495-506