InterPro domain: IPR028995

This superfamily represents a domain found in members of the glycosyl hydrolases families 57 and 38 [ 1 , 2 ]. This central domain adopts a structure consisting of three alpha helices and forms an immunoglobulin/albumin-binding domain-like fold. This domain can also be found in the C-terminal of the Alpha-amylase AmyC protein.

1. Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor. J. Biol. Chem. 278, 19378-86
2. The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation. J. Mol. Biol. 327, 631-44