InterPro domain: IPR028641

General Information

  • Identifier IPR028641
  • Description Protein RCC2
  • Number of genes 152
  • Gene duplication stats Loading...

Abstract

Protein RCC2 (also known as TD-60) interacts with microtubules and is required for completion of mitosis and cytokinesis [ 1 ]. It may function as a guanine nucleotide exchange factor for the small GTPase RAC1 [ 2 ].

This entry also includes some uncharacterised bacterial proteins.


1. The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression. Dev. Cell 5, 295-307

Species distribution

Gene table