InterPro domain: IPR028159

This entry represents the C-terminal domain of replication protein A (RPA) interacting protein (RIP). RPA is a single stranded DNA-binding protein involved in DNA replication, repair, and recombination [ 1 ]. RPA interacting protein is involved in the import of RPA into the nucleus [ 2 , 3 ]. The C-terminal domain contains a putative zinc finger [ 4 ].

1. Species-specific variation of RPA-interacting protein (RIP) splice isoforms. BMB Rep 42, 22-7
2. Nuclear import of RPA in Xenopus egg extracts requires a novel protein XRIPalpha but not importin alpha. EMBO J. 18, 4348-58
3. Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies. Mol. Cell. Biol. 25, 8202-14