InterPro domain: IPR027988

This entry represents the N-terminal alpha-helical domain of the BREVIS RADIX (BRX), which was characterised as being a transcription factor in plants regulating the extent of cell proliferation and elongation in the growth zone of the root [ 1 , 2 ]. BRX maintains a rate-limiting brassinosteroid biosynthesis enzyme expression to keep brassinosteroid biosynthesis above a critical threshold [ 3 ]. BRX has a ubiquitous, although quantitatively variable role in modulating the growth rate in both the root and the shoot [ 4 ].

This entry features a short alpha-helical domain, N-terminal to the repeated alpha-helices of the BRX domain ( IPR013591 ).

1. Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel regulator of cell proliferation and elongation in the root. Genes Dev. 18, 700-14
2. Characterization of the plant-specific BREVIS RADIX gene family reveals limited genetic redundancy despite high sequence conservation. Plant Physiol. 140, 1306-16
3. BREVIS RADIX is involved in cytokinin-mediated inhibition of lateral root initiation in Arabidopsis. Planta 229, 593-603
4. BRX promotes Arabidopsis shoot growth. New Phytol. 188, 23-9