InterPro domain: IPR027921

General Information

  • Identifier IPR027921
  • Description NOP protein chaperone 1
  • Number of genes 160
  • Gene duplication stats Loading...
  • Associated GO terms GO:0000492  

Abstract

This entry includes NOPCHAP1 from animals and New4 from fission yeast.

NOPCHAP1 is a client-loading PAQosome/R2TP complex cofactor that selects NOP58 to promote box C/D small nucleolar ribonucleoprotein (snoRNP) assembly [ 1 ]. The function of New4 is not clear.


1. NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis. Nucleic Acids Res 49, 1094-1113

Species distribution

Gene table