InterPro domain: IPR026951

This entry represents the U-box domain found in peptidyl-prolyl cis-trans isomerase like 2 subfamily members. They are peptidyl-prolyl cis-trans isomerases that accelerate the folding of proteins. They catalyse the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [ 1 , 2 ].

1. Identification and comparative analysis of sixteen fungal peptidyl-prolyl cis/trans isomerase repertoires. BMC Genomics 7, 244
2. A divergent multi-domain cyclophilin is highly conserved between parasitic and free-living nematode species and is important in larval muscle development. Mol. Biochem. Parasitol. 95, 215-27