InterPro domain: IPR026906

General Information

  • Identifier IPR026906
  • Description BspA type Leucine rich repeat region
  • Number of genes 191
  • Gene duplication stats Loading...

Abstract

This repeat is found in a large number of BSPA-like surface antigens from Trichomonas vaginalis.

This entry represents a leucine rich repeat. A leucine-rich repeat (LRR) is a protein structural motif that forms an alpha/beta horseshoe fold [ 1 , 2 ]. Leucine-rich repeats are frequently involved in the formation of protein protein interactions [ 3 , 4 ].


1. The leucine-rich repeat: a versatile binding motif. Trends Biochem. Sci. 19, 415-21
2. Structural principles of leucine-rich repeat (LRR) proteins. Proteins 54, 394-403
3. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 11, 725-32
4. A leucine-rich repeat peptide derived from the Drosophila Toll receptor forms extended filaments with a beta-sheet structure. FEBS Lett. 291, 87-91

Species distribution

Gene table