InterPro domain: IPR026895
General Information
- Identifier IPR026895
- Description ER membrane protein complex subunit 1
- Number of genes 178
- Gene duplication stats Loading...
- Associated GO terms GO:0072546
Abstract
ER membrane protein complex subunit 1 is a component of the ER membrane protein complex (EMC, composed of EMC1, EMC2, EMC3, EMC4, EMC5 and EMC6). In Saccharomyces cerevisiae, the EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER) [ 1 ].
1. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323, 1693-7
Species distribution
Gene table
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