InterPro domain: IPR026532

General Information

  • Identifier IPR026532
  • Description Ribosome biogenesis protein BRX1
  • Number of genes 192
  • Gene duplication stats Loading...

Abstract

This family consists of BRX1 and homologues. In yeast, BRX1 is part of a complex that also includes RPF1, RPF2 and SSF1 or SSF2. It is required for biogenesis of the 60S ribosomal subunit [ 1 ].


1. Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits. Biol. Chem. 382, 1637-47

Species distribution

Gene table

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