InterPro domain: IPR026260

General Information

  • Identifier IPR026260
  • Description Threonine synthase, bacterial/archaeal
  • Number of genes 7
  • Gene duplication stats Loading...
  • Associated GO terms GO:0009088   GO:0004795  

Abstract

Threonine synthase ( 4.2.3.1 ) catalyses the conversion of O-phospho-L-homoserine and water into L-threonine and orthophosphate, using pyridoxal phosphate as a cofactor. The pyridoxal-phosphate binding site is a Lys (K) residue. The enzyme is distantly related to the serine/threonine dehydratases which are also pyridoxal-phosphate dependent enzymes [ 1 ].

This entry represents the a group of threonine synthases from bacteria and archaea.


1. Evolution of biosynthetic pathways: a common ancestor for threonine synthase, threonine dehydratase and D-serine dehydratase. EMBO J. 5, 3013-9

Species distribution

Gene table