InterPro domain: IPR026206

General Information

  • Identifier IPR026206
  • Description HAUS augmin-like complex subunit 3
  • Number of genes 146
  • Gene duplication stats Loading...
  • Associated GO terms GO:0051225   GO:0070652  

Abstract

HAUS augmin-like complex subunit 3 (HAUS3) contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex [ 1 , 2 ]. AUGMIN subunit3 (AUG3) is a plant homologue of HAUS3 [ 3 ].


1. HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr. Biol. 19, 816-26
2. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc. Natl. Acad. Sci. U.S.A. 106, 6998-7003
3. Augmin plays a critical role in organizing the spindle and phragmoplast microtubule arrays in Arabidopsis. Plant Cell 23, 2606-18

Species distribution

Gene table