InterPro domain: IPR025962

General Information

  • Identifier IPR025962
  • Description SdpI/YhfL protein family
  • Number of genes 6
  • Gene duplication stats Loading...

Abstract

This family of proteins includes the SdpI and YhfL proteins from Bacillus subtilis. The SdpI protein is a multipass integral membrane protein that protects toxin-producing cells from being killed. Killing is mediated by the exported toxic protein SdpC an extracellular protein that induces the synthesis of an immunity protein [ 1 ].


1. A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin. Cell 124, 549-59

Species distribution

Gene table

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