InterPro domain: IPR025709

General Information

  • Identifier IPR025709
  • Description Leucyl-tRNA synthetase, editing domain
  • Number of genes 111
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006418   GO:0002161  

Abstract

This entry represents the editing domain (known as CP1 domain) of Leucyl-tRNA synthetase ( 6.1.1.4 ), which hydrolyses mischarged tRNALeu. In the case of Leucyl-tRNA synthetase, the beta-strands that link the CP1 domain to the aminoacylation core of the protein are also required for editing activity [ 1 ].


1. Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity. Biochemistry 46, 6258-67

Species distribution

Gene table

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