InterPro domain: IPR025709
General Information
- Identifier IPR025709
- Description Leucyl-tRNA synthetase, editing domain
- Number of genes 111
- Gene duplication stats Loading...
- Associated GO terms GO:0006418 GO:0002161
Abstract
This entry represents the editing domain (known as CP1 domain) of Leucyl-tRNA synthetase ( 6.1.1.4 ), which hydrolyses mischarged tRNALeu. In the case of Leucyl-tRNA synthetase, the beta-strands that link the CP1 domain to the aminoacylation core of the protein are also required for editing activity [ 1 ].
1. Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity. Biochemistry 46, 6258-67
Species distribution
Gene table
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