InterPro domain: IPR025697

The CLU domain (CLUstered mitochondria) is a eukaryotic domain found in highly conserved eukaryotic proteins required for correct mitochondrial dispersal [ 1 , 2 ]. The exact function of the domain is unknown [ 3 ].

1. The cluA- mutant of Dictyostelium identifies a novel class of proteins required for dispersion of mitochondria. Proc. Natl. Acad. Sci. U.S.A. 94, 7308-13
2. Mitochondrial membrane dynamics are altered in cluA- mutants of Dictyostelium. J. Muscle Res. Cell. Motil. 23, 829-38
3. Two novel Src homology 2 domain proteins interact to regulate dictyostelium gene expression during growth and early development. J. Biol. Chem. 285, 22927-35