InterPro domain: IPR025687

In fission yeast, this zinc-finger domain appears is the region of Pol3 that binds directly to the B-subunit, Cdc1 [ 1 ]. Pol delta is a hetero-tetrameric enzyme comprising four evolutionarily well-conserved proteins: the catalytic subunit Pol3 and three smaller subunits Cdc1, Cdc27 and Cdm1 [ 2 ].

1. Characterization of the POL3 gene product from Schizosaccharomyces pombe indicates inter-species conservation of the catalytic subunit of DNA polymerase delta. J. Mol. Biol. 222, 209-18
2. Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis. BMC Mol. Biol. 10, 82